Description

Molecular Details

• Molecular Formula: C149H246N44O42S

• Molecular Weight: ~ 3357.9 g/mol

• Peptide Type: Synthetic Growth Hormone-Releasing Hormone (GHRH) fragment analog

• Derivation: Fragment of human GHRH(1–44); Sermorelin represents the 1–29 amino acid sequence, which is the shortest fully functional segment of GHRH.

Mechanism of Action (Research Use Only)

Sermorelin functions by binding to GHRH receptors in the pituitary, stimulating endogenous growth hormone release.

Key points:

• Mimics natural hypothalamic GHRH signaling.

• Shorter half-life than Tesamorelin or CJC-1295 (approx. 10–20 minutes).

• Induces pulsatile GH release, more physiologically aligned than exogenous GH administration.

Research Applications

• Endocrine studies involving GH/IGF-1 dynamics.

• Growth and development research related to pituitary function.

• Anti-aging models: explored for potential regenerative effects.

• Metabolic investigations: studied in fat metabolism, lean body mass, and energy homeostasis.

Storage & Handling (Research Use Only)

• Form: Lyophilized peptide powder.

• Storage:

  • Lyophilized: −20 °C long term.

  • Reconstituted: 2–8 °C (stable ~7–10 days).

• Reconstitution: Sterile bacteriostatic water.

• Solubility: Fully water-soluble.

• Use: For laboratory research only. Not for human or veterinary use.