Description

Molecular Details

• Molecular Formula: C50H68N14O10

• Molecular Weight: ~ 1025.19 g/mol

• Peptide Type: Synthetic melanocortin receptor agonist

• Derivation: Modified analog of α-MSH (alpha-melanocyte-stimulating hormone)

Mechanism of Action (Research Use Only)

PT-141 primarily acts as an agonist of melanocortin receptors (MC1R, MC3R, MC4R, MC5R), with a strong emphasis on MC4R.

Key points:

• Unlike PDE5 inhibitors (e.g., sildenafil), PT-141 works directly on the nervous system pathways rather than vascular pathways.

• In preclinical studies, it has been shown to modulate sexual arousal centers in the central nervous system.

• Also studied for energy balance, appetite regulation, and neuroendocrine signaling.

Research Applications

• Sexual function research: Studied for effects on libido and arousal mechanisms.

• Neurological models: Investigation of melanocortin pathways in CNS signaling.

• Metabolic studies: Potential roles in appetite suppression and energy expenditure.

Storage & Handling (Research Use Only)

• Form: Lyophilized peptide powder.

• Storage:

  • Lyophilized: −20 °C long term.

  • Reconstituted: 2–8 °C (stable ~7–10 days).

• Reconstitution: Sterile bacteriostatic water.

• Solubility: Fully water-soluble.

• Use: For laboratory research only. Not for human or veterinary use.