Description

Molecular Details of NAD⁺

• Molecular Formula:
  C21H27N7O14P2

• Molecular Weight (Monoisotopic):
  663.43 g/mol

• Compound Type:
  Endogenous coenzyme
  Found in all living cells, essential for redox reactions and energy metabolism

• Structure:
  Dinucleotide composed of adenosine monophosphate (AMP) and nicotinamide mononucleotide (NMN) linked through phosphate groups

🧬 Mechanism of Action (Research Use Only):

• Acts as a coenzyme in redox reactions, cycling between NAD⁺ (oxidized) and NADH (reduced)

• Essential for ATP production in glycolysis, the Krebs cycle, and oxidative phosphorylation

• Cofactor for sirtuins and PARPs, regulating DNA repair, longevity, and cellular stress responses

• Central to mitochondrial function, metabolic health, and cell signaling

🧪 Research Applications:

• Aging and longevity studies (sirtuin activation, mitochondrial decline)

• Metabolic disorders (type 2 diabetes, obesity, insulin resistance)

• Neuroprotection (Parkinson’s, Alzheimer’s, cognitive decline)

• Cellular stress & repair (oxidative stress, DNA repair, inflammation)

• Investigated in combination with NMN and NR (nicotinamide riboside) supplementation models

📑 Storage & Handling (Research Use Only):

• Form: Powder or lyophilized crystalline solid

• Common Dosages (research vials): 50 mg, 100 mg, or 250 mg

• Storage:

  • Store at −20 °C, protected from light and moisture

  • Stable for extended periods in lyophilized form

  • Reconstituted solution should be stored at 2–8 °C, short-term

• Solubility: Water-soluble (stable in physiological buffers)

• Use: For laboratory research only. Not for human or veterinary use.