Description

Molecular Details of MOTS-c

• Molecular Formula:
  C60H91N13O20

• Molecular Weight (Monoisotopic):
  1479.47 g/mol

• Peptide Type:
  Mitochondria-derived peptide (MDP)
  Encoded within the mitochondrial 12S rRNA gene

• Amino Acid Sequence (16 aa):
  Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ser-Pro-Arg-Lys-Leu-Arg-Arg-Ala

🧬 Mechanism of Action (Research Use Only):

• Regulates cellular metabolism and stress response

• Enhances insulin sensitivity and glucose regulation

• Activates AMPK pathway → promotes fatty acid oxidation and mitochondrial biogenesis

• Functions as a mitokine, signaling between mitochondria and nucleus

• Studied for roles in longevity, metabolic health, and exercise adaptation

🧪 Research Applications:

• Metabolic disorders (insulin resistance, obesity, type 2 diabetes)

• Mitochondrial function and aging studies

• Exercise physiology (endurance, energy regulation)

• Neuroprotection and cognitive health

• Potential applications in age-related decline and longevity research

📑 Storage & Handling (Research Use Only):

• Form: Lyophilized peptide powder

• Common Dosages: 5 mg or 10 mg vials

• Storage:

  • Lyophilized: Store at −20 °C

  • Reconstituted: Store at 2–8 °C (stable for 7–10 days)

• Reconstitution: Sterile bacteriostatic water

• Solubility: Water-soluble under physiological pH

• Use: For laboratory research only. Not for human or veterinary use.