Description

Molecular Details

• Molecular Formula: C78H111N21O19

• Molecular Weight: ~ 1646.9 g/mol

• Peptide Type: Synthetic α-MSH (alpha-melanocyte-stimulating hormone) analog

• Derivation: Linear peptide analog of α-MSH, designed with improved stability and potency compared to the natural hormone.

Mechanism of Action (Research Use Only)

MT-1 binds primarily to the melanocortin-1 receptor (MC1R) on melanocytes.

Key points:

• Stimulates melanin production, increasing pigmentation.

• Acts with higher specificity for MC1R compared to MT-2, leading to fewer systemic effects.

• Investigated for photoprotection by increasing skin pigmentation and potentially reducing UV damage in models.

Research Applications

• Dermatological studies: Explored for use in pigmentation enhancement and photoprotection.

• Melanocyte biology: Useful in studying receptor-specific effects of α-MSH analogs.

• Skin cancer prevention models: Investigated for its ability to protect against UV-induced DNA damage.

Storage & Handling (Research Use Only)

• Form: Lyophilized peptide powder.

• Storage:

  • Lyophilized: −20 °C long term.

  • Reconstituted: 2–8 °C (stable ~7–10 days).

• Reconstitution: Sterile bacteriostatic water.

• Solubility: Fully water-soluble.

• Use: For laboratory research only. Not for human or veterinary use.