Description

Molecular Details

• Molecular Formula: C221H366N72O67S

• Molecular Weight: ~ 5135.9 g/mol

• Peptide Type: Synthetic Growth Hormone-Releasing Hormone (GHRH) analog

• Derivation: Modified from human GHRH(1–44) with a trans-3-hexenoic acid group at the N-terminus to improve stability.

Mechanism of Action (Research Use Only)

Tesamorelin mimics endogenous GHRH by stimulating the pituitary gland to release growth hormone (GH), which in turn elevates IGF-1 levels.

Key points:

• Enhances GH pulsatility similar to natural physiology.

• Modifications increase resistance to enzymatic degradation and extend half-life compared to native GHRH.

• Studied extensively in models of lipid metabolism and adipose tissue reduction.

Research Applications

• Metabolic and endocrine research: Effects on visceral adipose tissue reduction.

• Lipid metabolism studies: Potential influence on triglyceride breakdown and fat redistribution.

• GH/IGF-1 axis exploration: Investigated for roles in tissue regeneration, immune function, and anabolic processes.

Storage & Handling (Research Use Only)

• Form: Lyophilized peptide powder.

• Storage:

  • Lyophilized: −20 °C long term.

  • Reconstituted: 2–8 °C (stable ~7–10 days).

• Reconstitution: Sterile bacteriostatic water.

• Solubility: Fully water-soluble.

• Use: For laboratory research only. Not for human or veterinary use.