Description

Molecular Details

CJC-1295 (No DAC)

• Molecular Formula: C152H252N44O42

• Molecular Weight (Monoisotopic): 3367.84 g/mol

• Peptide Type: Growth Hormone Releasing Hormone (GHRH) analog

• Modification: No DAC (Drug Affinity Complex) → shorter half-life (~30 minutes), allowing for pulsatile GH release

Ipamorelin

• Molecular Formula: C38H49N9O5

• Molecular Weight (Monoisotopic): 711.85 g/mol

• Peptide Type: Growth Hormone Secretagogue (GHS)

• Selective Ghrelin receptor agonist (GHSR-1a) → stimulates GH release without affecting cortisol or prolactin

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🧬 Mechanism of Action (Research Use Only)

CJC-1295 (No DAC)

• Mimics natural GHRH → stimulates pituitary release of growth hormone (GH)

• Short-acting → promotes natural pulsatile secretion, closer to physiologic rhythm

Ipamorelin

• Binds to ghrelin receptor (GHSR-1a) in the pituitary

• Strong GH release with minimal side effects on appetite or stress hormones

• Provides synergy when combined with GHRH analogs like CJC-1295

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⚡ Synergistic Effects in Combination

• CJC-1295 (no DAC) provides the signal to initiate GH release

• Ipamorelin enhances and prolongs that signal by stimulating ghrelin receptors

• Together → greater GH release than either alone, while maintaining a natural pulsatile pattern

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🧪 Research Applications

• Growth hormone regulation models

• Metabolic studies (insulin sensitivity, fat metabolism)

• Muscle and connective tissue regeneration

• Bone density and recovery research

• Anti-aging research (GH/IGF-1 pathways)

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📑 Storage & Handling (Research Use Only)

• Form: Lyophilized peptide powders (often sold as a blend)

• Common Dosages (research vials):

  • CJC-1295 (no DAC): 2 mg or 5 mg

  • Ipamorelin: 2 mg or 5 mg

• Storage:

  • Lyophilized: Store at −20 °C

  • Reconstituted: Store at 2–8 °C (stable 7–10 days)

• Reconstitution: Sterile bacteriostatic water

• Solubility: Both are water-soluble

• Use: For laboratory research only. Not for human or veterinary use.